The United States hold a commanding 9-3 lead over Great Britain and Ireland after the second day of the 40th Curtis Cup match at Quaker Ridge.
The hosts won the morning fourballs 3-0 before claiming two points from the afternoon foursomes.
Playing No.1 and No.2 ranked amateur golfers in the world, Lillia Vu and Jennifer Kupcho, Olivia Mehaffey and Sophie Lamb contributed GB&I’s only point winning 2&1.
The United States need only 1½ points from tomorrow’s singles matches to win the overall match.
The pairing of Mehaffey and Lamb, who won 1½ pints on the opening day, continued to be the highlight of the GB&I effort.
Mehaffey, who is undertaking a golf scholarship at Arizona State, was thrilled to take the afternoon match over the talented Vu and Kupcho.
“We played really well this afternoon. We played two amazing players so feels pretty good to get the win right now," said Mehaffey.
"Obviously, it's a little disappointing how the team has done but everyone will be pumped up tomorrow. We’ve got nothing to lose, we've got to go out all guns blazing and hopefully we can get a couple points on the board.”
Despite the result on Saturday the GB&I supporters were in fine voice with around 300 having made the trip from across the pond, something the team have appreciated, admitted Mehaffey.
"I told everyone to be so loud before we went out. It really helps, and we had a smile on our face the whole way around knowing that. Sophie has 20 family members, so that took care of a lot of it!
Lamb added, "They were just screaming walking down the fairway, so that got us really excited, and we wanted to give them something to cheer for."
Captain Elaine Farquharson-Black was disappointed with the result but said her team will be going out on Sunday with a fighting mentality. She said, “We definitely played better in the morning than we played in the afternoon.
"Olivia and Sophie played great golf but in the second match we were doing all right before losing five holes on the spin and then it got really ragged. You can’t get any momentum and they were always fighting it.
“I was disappointed because we didn't play to our own high standards and we didn't really put any pressure on the Americans in the second two matches.
“We can still do it. Every single one of them can beat every single one of the Americans. We've got to believe that and we've got to go out fighting.”
Olivia Mehaffey / Sophie Lamb (GB&I) vs. Jennifer Kupcho / Kristen Gillman (USA) – United States win 3&2.
Alice Hewson / Annabell Fuller (GB&I) vs. Lilia Vu / Mariel Galdiano (USA) – United States win 2&1.
Lily May Humphreys / Shannon McWilliam (GB&I) vs. Lucy Li / Andrea Lee (USA) – United States win 3&2.
Olivia Mehaffey / Sophie Lamb (GB&I) vs. Jennifer Kupcho / Lilia Vu (USA) – GB&I win 2&1.
Annabell Fuller / India Clyburn (GB&I) vs. Lauren Stephenson / Kristen Gillman – United States win 6&5.
Paula Grant / Shannon McWilliam (GB&I) vs. Lucy Li / Sophia Schubert – United States win 7&5.